Hypoxanthine: Structural Incompatibility With Thymine
Hypoxanthine, a purine base, is unable to bind to thymine, a pyrimidine base, in the context of DNA or RNA synthesis due to structural differences. Thymine typically pairs with adenine, while hypoxanthine resembles guanine. Furthermore, the absence of a methyl group on hypoxanthine, unlike thymine, prevents the formation of a stable hydrogen bond. Consequently, the … Read more